Tsaku was born in Tashkent, Uzbekistan. In 1991, Tsaku returned to his homeland and became an Instructor of painting and drawing at the Tashkent Academy of Art and Theater. In 2001 he returned to Israel to start a new line of works taking its motif in the Old Testament. Tsaku's paintings were acquired for the permanent collections of the Israel Museum and the President's Residence, both in Jerusalem.